01 October 2021

PhD Student

Equipe ReDD


Development of functional and virus resistant allele based on the eIF4E1 susceptibility by CRISPR-editing in plants.

Many crop cultures in the world are threatened by a large virus group, potyvirus, while we attempt at sustainable food production with less pesticide. Given that potyvirus utilizes plant’s eIF4E proteins to infect in their hosts, we are performing modifications in these proteins via CRISPR-Cas9 technologies in order to make them unavailable to the viruses. In this project, I will analyze the eIF4E-edited tomatoes to see the extent of established virus resistance as well as the function of the edited proteins in the plant’s system. Through this project, we can expect to have not only the resistant healthy tomato as a deliverable but also the better understanding in the mechanism of potyvirus infection and the functional role of eIF4E.

 Director: Jean-Luc Gallois and Marianne Mazier

Training and carrier

2021-present : Doctorat in Biologie Végétale, Ecole Doctorale Sciences de la Vie et de la Santé (EDSVS)- Aix-Marseille Université

2020-2021 : Master 2 Sciences et technologies de l'agriculture, de l'alimentation et de l'environnement / Parcours : Biologie et Biotechnologies Environnementales (BBE), Aix-Marseille Université

2016-2020 : Bachelor’s degree in Agricultural Sciences / Speciality: Agrobiology and Bioresources, Hokkaido University, Japan

Contact: kyoka.kuroiwa@inrae.fr

Publication date : 21 June 2023